发明授权
- 专利标题： 5-substituted-2-arylpyridines
- 专利标题（中）： 5-取代-2-芳基吡啶
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申请号： US10154396申请日： 2002-05-22
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公开(公告)号： US07223778B2公开(公告)日： 2007-05-29
- 发明人: Ge Ping , Taeyoung Yoon , Lu Yan Zhang , Raymond F. Horvath
- 申请人： Ge Ping , Taeyoung Yoon , Lu Yan Zhang , Raymond F. Horvath
- 申请人地址： US CT Branford
- 专利权人： Neurogen Corporation
- 当前专利权人： Neurogen Corporation
- 当前专利权人地址： US CT Branford
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 代理商 Peter F. Corless; Dwight D. Kim
- 主分类号： C07D213/02
- IPC分类号： C07D213/02 ; A61K31/44
摘要：
Novel 5-substituted-2-arylpyridine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyridine compounds provided herein are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided.Compounds provided are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.
公开/授权文献
- US20030152520A1 5-Substituted-2-arylpyridines 公开/授权日：2003-08-14
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