发明授权
US07223764B2 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound
有权
2,4-二（三氟乙氧基）吡啶化合物和含有该化合物的药物
- 专利标题： 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound
- 专利标题（中）： 2,4-二（三氟乙氧基）吡啶化合物和含有该化合物的药物
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申请号： US10883710申请日： 2004-07-06
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公开(公告)号： US07223764B2公开(公告)日： 2007-05-29
- 发明人: Kimiyuki Shibuya , Tadaaki Ohgiya , Takayuki Matsuda , Toru Miura
- 申请人： Kimiyuki Shibuya , Tadaaki Ohgiya , Takayuki Matsuda , Toru Miura
- 申请人地址： JP Nagoya-shi
- 专利权人： Kowa Co., Ltd.
- 当前专利权人： Kowa Co., Ltd.
- 当前专利权人地址： JP Nagoya-shi
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权： JP2003-192853 20030707
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D213/69 ; C07D401/12 ; C07D401/14 ; C07D403/12
摘要：
The present invention is directed to a 2,4-bis(trifluoroethoxy)pyridine compound represented by formula (1): (wherein X1 represents a fluorine atom or a hydrogen atom) or a salt thereof, and to a drug containing the compound or the salt as an active ingredient. The compound has metabolic resistance in human liver microsome, good absorbability upon oral administration, and excellent ACAT inhibitory activity.
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