Invention Grant
- Patent Title: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
- Patent Title (中): 抑制巨噬细胞迁移抑制因子及其鉴定方法
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Application No.: US11344938Application Date: 2006-01-31
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Publication No.: US07202248B2Publication Date: 2007-04-10
- Inventor: Federico C. A. Gaeta , Andrew Baird , Jerry Anchin , Wenbin Ying , Robert Florkiewicz , Jagadish Sircar , Sunil Kumar K. C.
- Applicant: Federico C. A. Gaeta , Andrew Baird , Jerry Anchin , Wenbin Ying , Robert Florkiewicz , Jagadish Sircar , Sunil Kumar K. C.
- Applicant Address: US CA San Diego
- Assignee: Avanir Pharmaceuticals
- Current Assignee: Avanir Pharmaceuticals
- Current Assignee Address: US CA San Diego
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61K31/496
- IPC: A61K31/496
Abstract:
Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.
Public/Granted literature
- US20060205734A1 Inhibitors of macrophage migration inhibitory factor and methods for identifying the same Public/Granted day:2006-09-14
Information query
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