Invention Grant
- Patent Title: Methods of increasing distribution of nucleic acids
- Patent Title (中): 增加核酸分布的方法
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Application No.: US10132681Application Date: 2002-04-25
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Publication No.: US07182944B2Publication Date: 2007-02-27
- Inventor: Krys Bankiewicz
- Applicant: Krys Bankiewicz
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Needle & Rosenberg, P.C.
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00
Abstract:
This invention provides a method of increasing the volume of distribution of a nucleic acid encoding a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a nucleic acid encoding a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the nucleic acid encoding a therapeutic agent in the tissue.
Public/Granted literature
- US20020187127A1 Methods of increasing distribution of nucleic acids Public/Granted day:2002-12-12
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