发明授权
- 专利标题: Conserved motif of hepatitis C virus E2/NS1 region
- 专利标题(中): 丙型肝炎病毒E2 / NS1区域的保守主题
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申请号: US08437952申请日: 1995-05-09
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公开(公告)号: US07098303B1公开(公告)日: 2006-08-29
- 发明人: Amy J. Weiner , Michael Houghton
- 申请人: Amy J. Weiner , Michael Houghton
- 申请人地址: US CA Emeryville
- 专利权人: Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人: Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人地址: US CA Emeryville
- 代理商 Roberta L. Robins; Michael J. Moran; Alisa A. Harbin
- 主分类号: C07K14/18
- IPC分类号: C07K14/18 ; A61K39/29
摘要:
Immunogenic polypeptides comprising hepatitis C virus (HCV) immunogens are described. The HCV immunogen comprises the amino acid sequence Xaa-Thr-Xaa-Val-Thr-Gly-Gly-Xaa-Ala-Ala-Arg-Thr-Thr-Xaa-Gly-Xaa-Xaa-Ser-Leu-P he-Xaa-Xaa-Gly-Xaa-Ser-Gln-Xaa-Ile-Gln-Leu-Ile (SEQ ID NO:8). The immunogenic polypeptide can be coupled to a bacterial toxoid, such as a diphtheria toxoid.
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