发明授权
- 专利标题： Receptor-type phosphotyrosine phosphatase-kappa antibodies
- 专利标题（中）： 受体型磷酸酪氨酸磷酸酶κ抗体
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申请号： US09887669申请日： 2001-10-01
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公开(公告)号： US07056508B2公开(公告)日： 2006-06-06
- 发明人: Joseph Schlessinger , Jan M. Sap , Axel Ullrich , Wolfgang Vogel , Miriam Fuchs
- 申请人： Joseph Schlessinger , Jan M. Sap , Axel Ullrich , Wolfgang Vogel , Miriam Fuchs
- 申请人地址： US NY New York DE Munich
- 专利权人： New York University,Max Planck Gesellschaft Forgerung der Wissenschaften
- 当前专利权人： New York University,Max Planck Gesellschaft Forgerung der Wissenschaften
- 当前专利权人地址： US NY New York DE Munich
- 代理商 Nicholas I. Slepchuk, Jr.; Gregg C. Benson; Beth A. Burrous
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12P21/08 ; C12P21/02 ; G01N33/567 ; C07K1/00
摘要：
A novel receptor-type protein tyrosine phosphatase-κ (RPTPκ) protein or glycoprotein and the DNA coding therefor is expressed in a wide variety of mammalian tissues. The RPTPκ protein or glycoprotein may be produced by recombinant means. Antibodies to the protein, methods for measuring the quantity of the protein, methods for screening compounds, such as drugs, which can bind to the protein and inhibit or stimulate their enzymatic activity, are provided. Further, methods for inhibiting homophilic binding of Type II RPTP, especially RPTPκ molecules are provided.
公开/授权文献
- US20020082397A1 NOVEL RECEPTOR-TYPE PHOSPHOTYROSINE PHOSPHATASE-KAPPA 公开/授权日：2002-06-27
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