A cartridge-loading device is provided, to which a cartridge charged with a fluid material is loaded. The device comprises a cylindrical device body, piston, and nozzle. Both ends of the device body are opened to provide a bore therethrough. The cartridge is inserted into the bore. A notch is formed at an end portion of the device body. The piston, which is slidably arranged in the bore, is used for pushing the cartridge for ejecting the fluid material. The nozzle is detachably fitted into the opening of one end of the device body. The one end is located oppositely to the piston and have the notch formed thereat. Further, the cartridge has a cartridge body covered tightly by a cover member having one end protrude from an end of the cartridge body on an ejecting side thereof.