A move engine and operating system transparently reconfigure physical memory to accomplish addition, subtraction, or replacement of a memory module. The operating system stores FROM and TO real addresses in unique fields in memory that are used to virtualize the physical address of the memory module being reconfigured and provide the reconfiguration in real-time through the use of hardware functionality and not software. Using the FROM and TO real addresses to select a source and a target, the move engine copies the contents of the memory module to be removed or reconfigured into the remaining or inserted memory module. Then, the real address associated with the reconfigured memory module is re-assigned to the memory module receiving the copied contents, thereby creating a virtualized physical mapping from the addressable real address space being utilized by the operating system into a virtual physical address space. During the process of moving the memory contents, the operating system stalls. Write memory requests addressed to the real address space currently associated with the sourcing memory module indicated by either the FROM or TO real address space. As will be appreciated, a memory module can be inserted, removed or replaced in physical memory without the operating system having to stop all memory operations in the memory to accomplish the physical memory change.