发明授权
US06821987B2 Quinoline derivatives and quinazoline derivatives having azolyl group
有权
喹啉衍生物和具有唑基的喹唑啉衍生物
- 专利标题: Quinoline derivatives and quinazoline derivatives having azolyl group
- 专利标题(中): 喹啉衍生物和具有唑基的喹唑啉衍生物
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申请号: US10132473申请日: 2002-04-26
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公开(公告)号: US06821987B2公开(公告)日: 2004-11-23
- 发明人: Kazuo Kubo , Teruyuki Sakai , Rika Nagao , Yasunari Fujiwara , Toshiyuki Isoe , Kazumasa Hasegawa
- 申请人: Kazuo Kubo , Teruyuki Sakai , Rika Nagao , Yasunari Fujiwara , Toshiyuki Isoe , Kazumasa Hasegawa
- 优先权: JP2001-132775 20010427
- 主分类号: C07D40112
- IPC分类号: C07D40112
摘要:
An object of the present invention is to provide compounds having potent antitumor activity. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts or solvates thereof: wherein X and Z represent CH or N; Y represents O or S; R1, R2, and R3 represent H, alkoxy or the like; R4 represents H; R5, R6, R7, and R8 represent H, halogen, alkoxy or the like; R9 and R10 represent H, alkyl or the like; and R11 represents optionally substituted azolyl.
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