A method of driving an AMEL display. The AMEL display includes a pixel having a first transistor, a second transistor, a capacitor, and an organic light emitting diode (O-LED). A frame time interval for the invention includes at least a first sub-interval and a second sub-interval. The method includes the following steps. First, during the first sub-interval, apply a first pulse to the scan lines sequentially and apply corresponding data signals to the data lines. Next, during the second sub-interval, apply a second pulse to the scan lines sequentially so as to turn on the first transistors and apply a prevention signal to the data lines so as to turn off the corresponding second transistors.