Invention Grant
- Patent Title: Alpha-amino-acid compounds
- Patent Title (中): α-氨基酸化合物
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Application No.: US10146272Application Date: 2002-05-15
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Publication No.: US06706742B2Publication Date: 2004-03-16
- Inventor: Guillaume De Nanteuil , Bernard Portevin , Alain Benoist , Nigel Levens , Olivier Nosjean , Bernadette Husson-Robert , Michelle Boulanger
- Applicant: Guillaume De Nanteuil , Bernard Portevin , Alain Benoist , Nigel Levens , Olivier Nosjean , Bernadette Husson-Robert , Michelle Boulanger
- Priority: FR0106375 20010515
- Main IPC: C07D27704
- IPC: C07D27704

Abstract:
Compound selected from those of formula (I): wherein: represents an optionally substituted 5-membered nitrogen-containing heterocycle, Ak represents an alkylene chain, X represents a single bond or phenylene, R1 and R2, which may be identical or different, each represent hydrogen or alkyl, R3 represents alkyl, nitro or cyano, Y represents NR4 or CHNO2, R4 represents hydrogen or alkyl, its tautomers when they exist, its optical isomers, and addition salts thereof with a pharmaceutically acceptable acid, with the exclusion of compounds wherein, simultaneously, represents an unsubstituted 5-membered nitrogen-containing heterocycle, Ak represents —(CH2)3—, X represents a single bond, Y represents NH and R3 represents nitro. Medicinal products containing the same which are useful as dipeptidyl peptidase IV inhibitors.
Public/Granted literature
- US20030078247A1 Alpha-amino-acid compounds Public/Granted day:2003-04-24
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