发明授权
US06696447B2 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
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羟苯基 - 哌嗪基 - 甲基 - 苯甲酰胺衍生物用于治疗疼痛
- 专利标题: Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
- 专利标题(中): 羟苯基 - 哌嗪基 - 甲基 - 苯甲酰胺衍生物用于治疗疼痛
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申请号: US10240037申请日: 2002-09-27
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公开(公告)号: US06696447B2公开(公告)日: 2004-02-24
- 发明人: William Brown , Niklas Plobeck , Christopher Walpole
- 申请人: William Brown , Niklas Plobeck , Christopher Walpole
- 优先权: SE0001209 20000404
- 主分类号: A61K31496
- IPC分类号: A61K31496
摘要:
The present application describes compounds of general formula I where R1 is selected from any one of pyridinyl, thienyl, furanyl, imidazolyl, and triazolyl; and where each R1 heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the heteroaromatic ring may take place in any position on the ring system. The invention also includes enantiomers, salts and pharmaceutical compositions containing the compounds. The compounds may be used in treating patients for pain.
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