A diagnostic system for use in a process control system collects and stores in a database information pertaining to the operation of the process control system, and that uses an expert engine to apply rules for analysis to the information in the database to determine solutions to problems. The database stores various types of information such as event and alarm data, notices of scheduled maintenance and changes to operating parameters, and historical data related to previous changes to the process control system that are relevant to determining both the source of the problems detected in the process control system and the steps necessary to either further analyze or correct the detected problems. The diagnostic system identifies the source of the problem and identifies and runs the appropriate analytical tools or takes remedial measures based on the rules for analysis for the expert engine.