Nanostructured non-equilibrium, non-stoichiometric materials and device made using the nanonostructured non-equilibrium non-stoichiometric materials are provided. Applications and methods of implementing such devices and applications are also provided. More specifically, the specifications teach the use of nanostructured non-equilibrium, non-stoichiometric materials in polymer and plastic filler applications, electrical devices, magnetic products, fuels, biomedical applications, markers, drug delivery, optical components, thermal devices, catalysts, combinatorial discovery of materials, and various manufacturing processes.