Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses

发明授权

US06596536B1 Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses 失效

标题翻译：编码人T淋巴细胞受体的α链的可变区的核苷酸序列，相应的肽段以及诊断和治疗用途

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专利标题： Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
专利标题（中）： 编码人T淋巴细胞受体的α链的可变区的核苷酸序列，相应的肽段以及诊断和治疗用途
申请号： US08442001

申请日： 1995-05-16
公开(公告)号： US06596536B1

公开(公告)日： 2003-07-22
发明人: Thierry Hercend , Frederic Triebel , Sergio Roman-Roman , Laurent Ferradini
申请人： Thierry Hercend , Frederic Triebel , Sergio Roman-Roman , Laurent Ferradini
优先权： FR9101487 19910208; FR9104527 19910412
主分类号： C07K1628
IPC分类号： C07K1628

Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses

摘要：

An isolated antibody that specifically binds a peptide coded by a nucleotide sequence coding for a variable region of &agr; chain of an human T lymphocyte receptor, said nucleotide sequence having a nucleotide sequence chosen from any of: V&agr; segments having any one of the sequences SEQ ID Nos. 1 to 11 or J&agr; segments having one of the sequence SEQ ID Nos. 13 or 15 to 19 and hybridomas producing said antibodies.

摘要（中）：

一种分离的抗体，其特异性结合由编码人T淋巴细胞受体的α链的可变区的核苷酸序列编码的肽，所述核苷酸序列具有选自以下任何一个的核苷酸序列：具有序列SEQ ID 具有序列SEQ ID No.13或15至19之一的Nos.1至11或Jalpha片段和产生所述抗体的杂交瘤。

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