发明授权
US06539309B1 Crystallizable farnesyl protein transferase compositions, crystals thereby obtained, and methods for use
失效
可结晶的法呢基蛋白转移酶组合物，由此获得的晶体，以及使用方法
- 专利标题： Crystallizable farnesyl protein transferase compositions, crystals thereby obtained, and methods for use
- 专利标题（中）： 可结晶的法呢基蛋白转移酶组合物，由此获得的晶体，以及使用方法
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申请号： US09364182申请日： 1999-07-29
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公开(公告)号： US06539309B1公开(公告)日： 2003-03-25
- 发明人: Corey Strickland , Zhen Wu , William T. Windsor , Patricia C. Weber
- 申请人： Corey Strickland , Zhen Wu , William T. Windsor , Patricia C. Weber
- 主分类号： G01N3348
- IPC分类号： G01N3348
摘要：
The present invention relates to compositions and crystals of farnesyl protein transferase and farnesyl protein transferase in complex with substrates and inhibitors. Also disclosed are crystallization conditions for these compositions and their use for structural determination of FPT:FPP/FPP analog:peptide/inhibitor complexes.
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