发明授权
- 专利标题： Therapeutic uses of il-1 receptor antagonist
- 专利标题（中）： il-1受体拮抗剂的治疗用途
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申请号： US09576755申请日： 2000-05-22
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公开(公告)号： US06497870B1公开(公告)日： 2002-12-24
- 发明人: John Ford , Alice Suk-Yue Ho
- 申请人： John Ford , Alice Suk-Yue Ho
- 主分类号： A61K4500
- IPC分类号： A61K4500
摘要：
The present invention provides novel therapeutic methods of administering an amount of IL-1Ra to treat IL-18 related disorders. Specifically, the method involves treating IL-18 related disorders such as liver injury, hepatis, hemophagocytic lymphohistiocytosis, multiple sclerosis, tumors, cytotoxicity resulting from antitumor therapy, or other autoimmune disorders with a therapeutically effective amount of IL-1ra, and optionally measuring IFN-&ggr; and IL-18 activity from human samples.
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