Invention Grant
US06472431B2 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
有权
用于治疗发作性睡眠的γ-羟基丁酸盐的微生物健康和稳定的溶液
- Patent Title: Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
- Patent Title (中): 用于治疗发作性睡眠的γ-羟基丁酸盐的微生物健康和稳定的溶液
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Application No.: US09470570Application Date: 1999-12-22
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Publication No.: US06472431B2Publication Date: 2002-10-29
- Inventor: Harry Cook , Martha Hamilton , Douglas Danielson , Colette Goderstad , Dayton Reardan
- Applicant: Harry Cook , Martha Hamilton , Douglas Danielson , Colette Goderstad , Dayton Reardan
- Main IPC: A61K3119
- IPC: A61K3119
Abstract:
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
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