发明授权
- 专利标题： Compounds useful for inhibition of farnesyl protein transferase
- 专利标题（中）： 可用于抑制法呢基蛋白转移酶的化合物
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申请号： US09797081申请日： 2001-03-01
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公开(公告)号： US06387905B2公开(公告)日： 2002-05-14
- 发明人: F George Njoroge , Arthur G. Taveras , Ronald J. Doll , Tarik Lalwani , Carmen Alvarez , Stacy W. Remiszewski
- 申请人： F George Njoroge , Arthur G. Taveras , Ronald J. Doll , Tarik Lalwani , Carmen Alvarez , Stacy W. Remiszewski
- 主分类号： A61K31496
- IPC分类号： A61K31496
摘要：
Novel compounds of the formula: are disclosed. Compounds of Formula 1.0 are represented by the compounds of formulas: wherein R1, R3 and R4 are each independently selected from halo. Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.
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