发明授权
US06281357B1 Process for the production of indole derivatives 失效
吲哚衍生物生产工艺

  • 专利标题: Process for the production of indole derivatives
  • 专利标题(中): 吲哚衍生物生产工艺
  • 申请号: US09381072
    申请日: 2000-03-24
  • 公开(公告)号: US06281357B1
    公开(公告)日: 2001-08-28
  • 发明人: David Charles Waite
  • 申请人: David Charles Waite
  • 优先权: GB9714383 19970708
  • 主分类号: C07D20914
  • IPC分类号: C07D20914
Process for the production of indole derivatives
摘要:
The invention provides a process for the production of a compound of formula I, which comprises reacting a compound of formula II with a compound of formula III, in the presence of a strong base and a palladium(0) catalyst, at an elevated temperature, in a solvent which does not adversely affect the reaction. Compounds of formula I may be further processed to compounds of formula V, which are useful in the treatment of inter alia migraine.
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