A method of manufacturing a cylindrical non-aqueous electrolyte secondary cell according to the present invention comprises a first step of forming a lead-attaching area on which an active material layer is not formed, in a positive electrode wherein a positive electrode active material layer is formed on both sides of the positive electrode current collector and a negative electrode wherein a negative electrode active material layer is formed on both sides of the negative electrode current collector, and winding the positive electrode and the negative electrode with disposing a separator therebetween so that the lead-attaching areas are protruded from the edges of the separator, and a second step of disposing a lead at an end part of the lead-attaching area with interposing a metal plate having a multiplicity of holes, and thereafter laser-welding the lead and the metal plate and the lead-attaching area by applying a laser beam with a spot diameter larger than a hole diameter of the metal plate. According to the present invention, it is feasible to laser-weld a lead to a lead-attaching area without fear of a short circuit resulting from the fusion in an electrode assembly caused by a laser beam.