Invention Grant
US6117901A N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions
comprising same, and methods for use
失效
N-(芳基/杂芳基乙酰基)氨基酸酯,包含其的药物组合物和使用方法
- Patent Title: N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use
- Patent Title (中): N-(芳基/杂芳基乙酰基)氨基酸酯,包含其的药物组合物和使用方法
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Application No.: US976179Application Date: 1997-11-21
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Publication No.: US6117901APublication Date: 2000-09-12
- Inventor: Jing Wu , Eugene D. Thorsett , Jeffrey S. Nissen , Thomas E. Mabry , Lee H. Latimer , Varghese John , Lawrence Y. Fang , James E. Audia
- Applicant: Jing Wu , Eugene D. Thorsett , Jeffrey S. Nissen , Thomas E. Mabry , Lee H. Latimer , Varghese John , Lawrence Y. Fang , James E. Audia
- Applicant Address: CA South San Francisco IN Indianapolis
- Assignee: Athena Neurosciences, Inc.,Eli Lilly & Company
- Current Assignee: Athena Neurosciences, Inc.,Eli Lilly & Company
- Current Assignee Address: CA South San Francisco IN Indianapolis
- Main IPC: A61K31/198
- IPC: A61K31/198 ; A61K31/223 ; A61K31/277 ; A61K31/16
Abstract:
Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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