Invention Grant
- Patent Title: Prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections
- Patent Title (中): 前列腺衍生物及其与抗生素的组合治疗细菌感染
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Application No.: US011457Application Date: 1998-04-23
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Publication No.: US6040336APublication Date: 2000-03-21
- Inventor: Peter Scholz , Jorg Weber , Klemens Angstwurm
- Applicant: Peter Scholz , Jorg Weber , Klemens Angstwurm
- Applicant Address: DEX Berlin
- Assignee: Schering Aktiengesellschaft
- Current Assignee: Schering Aktiengesellschaft
- Current Assignee Address: DEX Berlin
- Priority: DEX19530884 19950811
- Main IPC: A61K47/40
- IPC: A61K47/40 ; A61K31/00 ; A61K31/557 ; A61K31/5575 ; A61K31/5578 ; A61K31/558 ; A61K31/5585 ; A61K45/00 ; A61P25/00 ; A61P31/00 ; A61P31/04 ; A61K31/34 ; A61K31/19 ; A61K31/21
Abstract:
A method is described for treating bacterially induced meningitis, comprising administering a prostane derivative of formula I or Ia ##STR1## wherein X.sup.1, X.sup.2, X.sup.3, X.sup.4, X.sup.5, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as described below, and the --O--R.sup.3 -- group is in the .alpha.- or .beta.-configuration. The prostane derivative can optionally comprise or serve as an adjuvant, and it can be administered in combination with an antiobiotic.
Public/Granted literature
- US5536623A Method of producing highly water-soluble cyclodextrin complex Public/Granted day:1996-07-16
Information query
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