Invention Grant
- Patent Title: Quinoline leukotriene antagonists
- Patent Title (中): 喹啉白三烯拮抗剂
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Application No.: US37949Application Date: 1998-03-10
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Publication No.: US5952347APublication Date: 1999-09-14
- Inventor: Byron H. Arison , Thomas A. Baillie , Suresh K. Balani , Claude Dufresne
- Applicant: Byron H. Arison , Thomas A. Baillie , Suresh K. Balani , Claude Dufresne
- Applicant Address: NJ Rahway
- Assignee: Merck & Co., Inc.
- Current Assignee: Merck & Co., Inc.
- Current Assignee Address: NJ Rahway
- Main IPC: C07D215/18
- IPC: C07D215/18 ; A61K31/47 ; C07D215/14 ; C07D215/36
Abstract:
Compounds of Formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
Public/Granted literature
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