Invention Grant
- Patent Title: Computational analysis of nucleic acid information defines binding sites
- Patent Title (中): 核酸信息的计算分析定义了结合位点
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Application No.: US494115Application Date: 1995-06-23
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Publication No.: US5867402APublication Date: 1999-02-02
- Inventor: Thomas D. Schneider , Peter K. Rogan
- Applicant: Thomas D. Schneider , Peter K. Rogan
- Applicant Address: DC Washington
- Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Department of Health and Human Services
- Current Assignee Address: DC Washington
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G06F19/18 ; G06F19/22 ; G06T7/00 ; G06F17/16
Abstract:
In accordance with the present invention, binding sites are defined based upon the individual information content of a particular site of interest. Substitutions within the binding site sequences can be analyzed to determine whether the substitution will cause a deleterious mutation or a benign polymorphism. In addition, new binding sites can be identified using individual information content. Further a computer system is described for determining and displaying individual information content of a binding site sequence.
Information query
