Invention Grant
- Patent Title: Methods and compositions useful for inhibition of angiogenesis
- Patent Title (中): 用于抑制血管生成的方法和组合物
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Application No.: US366665Application Date: 1994-12-30
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Publication No.: US5766591APublication Date: 1998-06-16
- Inventor: Peter Brooks , David A. Cheresh
- Applicant: Peter Brooks , David A. Cheresh
- Applicant Address: CA La Jolla
- Assignee: The Scripps Research Institute
- Current Assignee: The Scripps Research Institute
- Current Assignee Address: CA La Jolla
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N15/02 ; A61K38/00 ; A61K39/395 ; A61K45/00 ; A61P27/02 ; A61P29/00 ; A61P35/00 ; C07K14/705 ; C07K14/78 ; C07K16/28 ; C07K16/30 ; C12P21/08 ; C07K7/00 ; C07K14/745
Abstract:
The present invention describes methods for inhibiting angiogenesis in tissues using vitronectin .alpha..sub.v .beta..sub.3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing .alpha..sub.v .beta..sub.3 antagonists.
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