发明授权
US5716994A Antitumor and antileukaemic substances, their preparation and
pharmaceutical compositions containing them
失效
抗肿瘤药和抗白血病药物，其制剂和含有它们的药物组合物
- 专利标题： Antitumor and antileukaemic substances, their preparation and pharmaceutical compositions containing them
- 专利标题（中）： 抗肿瘤药和抗白血病药物，其制剂和含有它们的药物组合物
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申请号： US750838申请日： 1996-12-19
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公开(公告)号： US5716994A公开(公告)日： 1998-02-10
- 发明人: Jean Leboul , Jean Provost
- 申请人： Jean Leboul , Jean Provost
- 申请人地址： FRX Antony
- 专利权人： Rhone-Poulenc Rorer S.A.
- 当前专利权人： Rhone-Poulenc Rorer S.A.
- 当前专利权人地址： FRX Antony
- 优先权： FRX9407701 19940623; FRX9500160 19950109
- 主分类号： A61K36/00
- IPC分类号： A61K36/00 ; A61K31/085 ; A61K31/12 ; A61P1/00 ; A61P13/02 ; A61P15/00 ; A61P17/00 ; A61P35/00 ; A61P35/02 ; C07C41/34 ; C07C43/23 ; C07C45/78 ; C07C45/79 ; C07C49/753
摘要：
(3-hydroxy-4-methoxybenzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexahydroinden-4-one of formula (I): ##STR1## and 3-(3-hydroxy-4-methoxybenzyl)-4-hydroxy-7-methyl-1-vinylindan of formula (II): ##STR2## as well as their stereoisomeric forms are disclosed. Also disclosed are a process for producing these compounds from the plant Ottelia alismoides and pharmaceutical compositions containing them. The novel compounds of formulas (I) and (II) have remarkable antitumor and antileukaemic properties.
公开/授权文献
- US5187346A Laser welding method 公开/授权日：1993-02-16
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