Invention Grant
- Patent Title: Tricyclic inhibitors of the GPII.sub.b III.sub.a receptor
- Patent Title (中): GPIIbIIIa受体的三环抑制剂
-
Application No.: US313069Application Date: 1994-09-26
-
Publication No.: US5705890APublication Date: 1998-01-06
- Inventor: Brent K. Blackburn , Kirk Robarge , Todd C. Somers
- Applicant: Brent K. Blackburn , Kirk Robarge , Todd C. Somers
- Applicant Address: CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: CA South San Francisco
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61P7/02 ; C07D487/04 ; C07D498/04 ; C07D507/02 ; C07D513/04
Abstract:
A tricylic benzodiazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
Public/Granted literature
- US5051799A Digital output transducer Public/Granted day:1991-09-24
Information query
