发明授权
- 专利标题： Tricyclic inhibitors of the GPII.sub.b III.sub.a receptor
- 专利标题（中）： GPIIbIIIa受体的三环抑制剂
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申请号： US313069申请日： 1994-09-26
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公开(公告)号： US5705890A公开(公告)日： 1998-01-06
- 发明人: Brent K. Blackburn , Kirk Robarge , Todd C. Somers
- 申请人： Brent K. Blackburn , Kirk Robarge , Todd C. Somers
- 申请人地址： CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： CA South San Francisco
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61P7/02 ; C07D487/04 ; C07D498/04 ; C07D507/02 ; C07D513/04
摘要：
A tricylic benzodiazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
公开/授权文献
- US5051799A Digital output transducer 公开/授权日：1991-09-24
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