发明授权
- 专利标题： Spirovesamicols
-
申请号： US405491申请日： 1995-03-14
-
公开(公告)号： US5554752A公开(公告)日： 1996-09-10
- 发明人: Simon M. N. Efange , Stanley M. Parsons
- 申请人： Simon M. N. Efange , Stanley M. Parsons
- 申请人地址： MN Minneapolis
- 专利权人： Regents of the University of Minnesota
- 当前专利权人： Regents of the University of Minnesota
- 当前专利权人地址： MN Minneapolis
- 主分类号： A61K51/04
- IPC分类号： A61K51/04 ; C07D221/20 ; C07D401/04
摘要：
The compounds are vesamicol (hydroxylated phencyclidine (PCP) isomer trans-2-(4-phenyl-piperidino)cyclohexanol) derivatives with anticholinergic properties termed herein "spirovesamicols" which are spirofused piperidines. The compounds bind to the vesamicol receptor, a site on the cholinergic synaptic vesicle, which is associated with the vesicular transporter of acetylcholine.
公开/授权文献
信息查询
