发明授权
- 专利标题: Guanidine compounds
- 专利标题(中): 胍化合物
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申请号: US787374申请日: 1991-11-04
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公开(公告)号: US5494934A公开(公告)日: 1996-02-27
- 发明人: Charles Malen , Jean-Michel Lacoste , Guillaume de Nanteuil
- 申请人: Charles Malen , Jean-Michel Lacoste , Guillaume de Nanteuil
- 申请人地址: FRX Courbevoie
- 专利权人: Adir et Compagnie
- 当前专利权人: Adir et Compagnie
- 当前专利权人地址: FRX Courbevoie
- 优先权: FRX9014898 19901129
- 主分类号: A61K31/155
- IPC分类号: A61K31/155 ; A61K31/415 ; A61K31/495 ; A61P3/04 ; A61P3/08 ; A61P3/10 ; A61P9/00 ; A61P9/12 ; A61P11/00 ; A61P25/24 ; A61P25/26 ; C07C279/06 ; C07C279/08 ; C07C281/16 ; C07C281/18 ; C07D233/48 ; C07D233/50 ; C07D233/52 ; C07D239/14 ; C07D239/18
摘要:
A compound of formula (I): ##STR1## in which: R.sub.1 represents substituted or unsubstituted phenyl or (C.sub.3 -C.sub.7) cycloalkyl,R.sub.2 represents trifluoromethyl or (C.sub.3 -C.sub.4) cycloalkyl,A represents --CH.sub.2 --, --CH.dbd.N--, .dbd.N-- or --NH--,R.sub.3 and R.sub.4, which may be identical or different, represent hydrogen or linear or branched (C.sub.1 -C.sub.6) alkyl or, with the nitrogen atoms to which they are attached, form a 5- or 6-membered heterocycle,R represents either hydrogen in the case where A=--CH.sub.2 --, --CH.dbd.N-- or --NH--, or a bond of the group A when the latter is equal to .dbd.N--,its enantiomers and epimers as well as its addition salts with a pharmaceutically acceptable acid.Medicine products.
公开/授权文献
- US5752391A Refrigerating system 公开/授权日:1998-05-19
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