A multiple pharmaceutical syringe (2, 160, 402), especially useful for use in dispensing insulin, includes a body (4, 162, 404) housing first and second pharmaceutical-filled cartridges (30, 32; 182, 184; 478, 480). The cartridges are of the type with a septum (36, 190, 484) at one end and a piston (42, 48; 224, 225; 562, 564) at the other end with the liquid pharmaceutical (46, 48; 226, 228; 534, 536) between the two. The body also defines an accumulator chamber (10, 202, 654) within which an accumulator piston (26, 238, 464) is slidably mounted. The cartridge interiors are connected by a flow path (70, 752) to the accumulator chamber. Pressing on the cartridge pistons forces desired amounts of the liquids from the cartridge into the accumulator chamber. The mixed pharmaceutical is dispensed by driving the accumulator piston.