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US5225404A Methods of treating colon tumors with tumor-inhibiting camptothecin compounds 失效
用肿瘤抑制喜树碱化合物治疗结肠肿瘤的方法

Methods of treating colon tumors with tumor-inhibiting camptothecin
compounds
摘要:
The present invention provides methods of treating malignant colon and colo-rectal cancer in mammals, by reducing or inhibiting or retarding such colon cancer tumors in mammals. These methods employ the administration of a tumor-inhibiting or reducing camptothecin compound, e.g., 9-amino-20(RS)-camptothecin, 10,11-methylenedioxy-20(RS)-camptothecin, and the sodium salt of 10,11-methylenedioxy-20(RS)-camptothecin, or a combination thereof. Also provided are pharmaceutical formulations.
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