发明授权
US5164365A 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone and fragrance
compositions containing same
失效
1,1,2,3,3,6-十六烷基-4,5,6,7-四氢-2H-吲哚及其含有的芳香族组合物
- 专利标题: 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone and fragrance compositions containing same
- 专利标题(中): 1,1,2,3,3,6-十六烷基-4,5,6,7-四氢-2H-吲哚及其含有的芳香族组合物
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申请号: US661361申请日: 1991-02-26
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公开(公告)号: US5164365A公开(公告)日: 1992-11-17
- 发明人: Jean-Pierre Bachmann , Daniel Helmlinger , Mario Pesaro
- 申请人: Jean-Pierre Bachmann , Daniel Helmlinger , Mario Pesaro
- 申请人地址: NJ Clifton
- 专利权人: Givaudan Corporation
- 当前专利权人: Givaudan Corporation
- 当前专利权人地址: NJ Clifton
- 优先权: CHX663/90 19900302
- 主分类号: A61K8/34
- IPC分类号: A61K8/34 ; A61K8/35 ; A61K8/40 ; A61Q13/00 ; C07C35/23 ; C07C35/32 ; C07C45/27 ; C07C45/29 ; C07C45/51 ; C07C49/633 ; C07C211/60 ; C11B9/00
摘要:
The present invention concerns the novel odorant 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone, I, a process for the manufacture of I, novel intermediates used in the process and fragrance compositions containing I. ##STR1## The process for the manufacture of 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone comprises hydroborating 1,1,2,3,3,6-hexamethyl-4,7-dihydroindane and oxidizing the hydroboration product to 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone, or reductively alkylating, especially methylating, 5-nitro-1,1,2,3,3,6-hexamethylindane and converting the resulting 5-dialkyl-amino-1,1,2,3,3,6-hexamethylindane into 1,1,2,3,3,6-hexamethyl-4,5,6,7-tetrahydro-5-indanone by reduction of the benzene ring and hydrolysis of the resulting enamine.
公开/授权文献
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