发明授权
- 专利标题: Bone allograft material and method
- 专利标题(中): 骨同种异体移植材料及方法
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申请号: US437189申请日: 1989-11-16
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公开(公告)号: US5112354A公开(公告)日: 1992-05-12
- 发明人: Bryan S. Sires
- 申请人: Bryan S. Sires
- 申请人地址: IL Evanston
- 专利权人: Northwestern University
- 当前专利权人: Northwestern University
- 当前专利权人地址: IL Evanston
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61F2/28 ; A61F2/30 ; A61F2/46 ; A61L27/36
摘要:
A textured, demineralized, and unitary mammalian bone section for providing a rigid, foraminous, collagen scaffold for allogenic skeletal reconstruction. The allograft is prepared by treating a section of cadaver bone to remove all soft tissue, then texturing the bone surface to produce a pattern of holes of selected size, density, and depth, and finally demineralizing the bone section to leave a rigid, insoluble collagen scaffold suitable for osteoinduction upon implantation. All such steps are performed with minimal denaturing of the extracellular matrix proteins which remain bound to the collagen scaffold and which are necessary to complete the process of new bone formation.
公开/授权文献
- US5588876A Fused electrical connectors 公开/授权日:1996-12-31
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