发明授权
US5096929A 2-amino-1,2,3,4-tetrahydronaphthalene derivatives with cardiovascular
activity, process for their preparation and pharmaceutical compositions
containing them
失效
具有心血管活性的2-氨基-1,2,3,4-四氢萘并噻吩衍生物,其制备方法和含有它们的药物组合物
- 专利标题: 2-amino-1,2,3,4-tetrahydronaphthalene derivatives with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them
- 专利标题(中): 具有心血管活性的2-氨基-1,2,3,4-四氢萘并噻吩衍生物,其制备方法和含有它们的药物组合物
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申请号: US544201申请日: 1990-06-26
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公开(公告)号: US5096929A公开(公告)日: 1992-03-17
- 发明人: Paolo Chiesi , Stefano Bongrani , Maurizio Delcanale , Vittorino Servadio
- 申请人: Paolo Chiesi , Stefano Bongrani , Maurizio Delcanale , Vittorino Servadio
- 申请人地址: ITX Parma
- 专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人地址: ITX Parma
- 优先权: ITX20996A/89 19890627
- 主分类号: A61K31/135
- IPC分类号: A61K31/135 ; A61P9/04 ; A61P9/08 ; C07C213/02 ; C07C217/74
摘要:
5,6-Dimethoxy-2-[2-(4-hydroxyphenyl)-2-hydroxy-2-methylethyl]amino- 1,2,3,4-tetrahydronaphthalene has inotropic and vasodilating activities and therefore can be used in the treatment of cardiocirculatory failure. The compound can be in the form of a single stereoisomer or as a mixture of two or more stereoisomers.
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