发明授权
US4985366A Process for the enzymatic resolution of the optical isomers of racemic
ester derivatives of 3-mercapto-2-alkyl-propionic acid
失效
用于酶解拆分3-巯基-2-烷基 - 丙酸的外消旋酯衍生物的光学异构体的方法
- 专利标题： Process for the enzymatic resolution of the optical isomers of racemic ester derivatives of 3-mercapto-2-alkyl-propionic acid
- 专利标题（中）： 用于酶解拆分3-巯基-2-烷基 - 丙酸的外消旋酯衍生物的光学异构体的方法
-
申请号： US357949申请日： 1989-05-30
-
公开(公告)号： US4985366A公开(公告)日： 1991-01-15
- 发明人: Daniele Bianchi , Pietro Cesti , Paolo Golini
- 申请人： Daniele Bianchi , Pietro Cesti , Paolo Golini
- 申请人地址： ITX
- 专利权人： Montedison S.p.A
- 当前专利权人： Montedison S.p.A
- 当前专利权人地址： ITX
- 优先权： ITX20834A/88 19880602
- 主分类号： C12P11/00
- IPC分类号： C12P11/00 ; C12P41/00
摘要：
The biotechnological resolution by means of stereoselective enzymatic thio-transesterification of the racemic mixture of the optical isomers of the compounds of formula (I): ##STR1## wherein: R, R' and R", alike or different form one another, represent a linear alkyl group of from C.sub.1 to C.sub.4, in the presence of an alcohol and an enzyme capable of selectively causing the reaction of thio-transesterification of the (L)-isomer to take place, with the (D)-isomer remaining substantially unchanged, and being then separated by means of per se known techniques.
公开/授权文献
信息查询
