发明授权
US4975467A Method of inhibiting interleukin-1 release and alleviating interleukin-1
mediated conditions
失效
抑制白细胞介素1释放和缓解白介素-1介导的病症的方法
- 专利标题： Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions
- 专利标题（中）： 抑制白细胞介素1释放和缓解白介素-1介导的病症的方法
-
申请号： US499567申请日： 1990-03-26
-
公开(公告)号： US4975467A公开(公告)日： 1990-12-04
- 发明人: George Ku , Niall Doherty
- 申请人： George Ku , Niall Doherty
- 申请人地址： OH Cincinnati
- 专利权人： Merrell Dow Pharmaceuticals Inc.
- 当前专利权人： Merrell Dow Pharmaceuticals Inc.
- 当前专利权人地址： OH Cincinnati
- 主分类号： A61K31/10
- IPC分类号： A61K31/10
摘要：
Methods useful for inhibiting the release of Interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1 mediated inflammation, comprising administration of an effective amount of an alkylidenedithiobis(substituted)phenol, preferably, 4,4'-(isopropylidenedithio(bis(2,6-di-tert-butyl) phenol, generically known as probucol.
信息查询
