发明授权
- 专利标题: Tricyclic aromatic compounds
- 专利标题(中): 三环芳香族化合物
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申请号: US894306申请日: 1986-08-07
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公开(公告)号: US4871865A公开(公告)日: 1989-10-03
- 发明人: O. William Lever, Jr. , Harry J. Leighton
- 申请人: O. William Lever, Jr. , Harry J. Leighton
- 申请人地址: NC Research Triangle Park
- 专利权人: Burroughs Wellcome Co.
- 当前专利权人: Burroughs Wellcome Co.
- 当前专利权人地址: NC Research Triangle Park
- 优先权: GBX8520662 19850817
- 主分类号: C07C59/86
- IPC分类号: C07C59/86 ; A61K31/00 ; A61K31/335 ; A61P11/00 ; A61P37/08 ; A61P43/00 ; C07C51/00 ; C07C65/36 ; C07C67/00 ; C07C229/34 ; C07C229/38 ; C07C231/00 ; C07C231/12 ; C07C237/20 ; C07C237/30 ; C07C253/00 ; C07C255/42 ; C07C255/58 ; C07D313/12 ; C07D313/14
摘要:
The present invention relates to compounds of formula I ##STR1## or a salt, ester or amide thereof; wherein R.sup.1 is --CH.sub.2 --CH.sub.2 --, CH.sub.2 --O-- or --O--CH.sub.2 --; R.sup.2 and R.sup.3 are the same or different and are each hydrogen, C.sub.1-4 alkyl or taken together with the nitrogen comprise a nitrogen-containing heterocyclic ring having four to six ring members; R.sup.4 is a single bond or a C.sub.1-7 bivalent aliphatic hydrocarbon group and may be joined to the aromatic ring system at the 2,3,8 or 9 positions; n is 0 to 3, and their use as anithistamine and antiasthma agents.
公开/授权文献
- US5855135A Horizontal metal extrusion press 公开/授权日:1999-01-05
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