Invention Grant
US4755528A High energy ionizing protective 2,3-diamino-1,4-butanedithiol;
4,5-diamino-1,2-dithiane; and N-acyl and N-alkyl derivatives thereof,
compositions and method of use therefor
失效
高能电离保护性2,3-二氨基-1,4-丁二硫醇; 4,5-二氨基-1,2-二噻烷; 和N-酰基和N-烷基衍生物,其组合物及其用途
- Patent Title: High energy ionizing protective 2,3-diamino-1,4-butanedithiol; 4,5-diamino-1,2-dithiane; and N-acyl and N-alkyl derivatives thereof, compositions and method of use therefor
- Patent Title (中): 高能电离保护性2,3-二氨基-1,4-丁二硫醇; 4,5-二氨基-1,2-二噻烷; 和N-酰基和N-烷基衍生物,其组合物及其用途
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Application No.: US42221Application Date: 1987-04-17
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Publication No.: US4755528APublication Date: 1988-07-05
- Inventor: Mark T. DuPriest , Billie M. York, Jr.
- Applicant: Mark T. DuPriest , Billie M. York, Jr.
- Applicant Address: TX Fort Worth
- Assignee: Alcon Laboratories, Inc.
- Current Assignee: Alcon Laboratories, Inc.
- Current Assignee Address: TX Fort Worth
- Main IPC: C07D339/08
- IPC: C07D339/08 ; A61K31/095 ; A61K31/385 ; C07C149/14
Abstract:
Disclosed are 2,3-diamino-1,4-butanedithiol; 4,5-diamino-1,2-dithiane; and their N-acyl and N-alkyl derivatives. Also disclosed are processes for preparing the disclosed compounds; pharmaceutical compositions comprising such compounds; and a method of treatment comprising administering such compounds and compositions when an antihypertensive effect or radioprotective effect is indicated.
Public/Granted literature
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