发明授权
US4659733A Method for treating hypertension with 2,3-diamino-1,4-butanedithiol;
4,5-diamino-1,2-dithiane; and N-acyl and N-alkyl derivatives thereof
失效
用2,3-二氨基-1,4-丁二硫醇治疗高血压的方法; 4,5-二氨基-1,2-二噻烷; 及其N-酰基及N-烷基衍生物
- 专利标题： Method for treating hypertension with 2,3-diamino-1,4-butanedithiol; 4,5-diamino-1,2-dithiane; and N-acyl and N-alkyl derivatives thereof
- 专利标题（中）： 用2,3-二氨基-1,4-丁二硫醇治疗高血压的方法; 4,5-二氨基-1,2-二噻烷; 及其N-酰基及N-烷基衍生物
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申请号： US678833申请日： 1984-12-06
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公开(公告)号： US4659733A公开(公告)日： 1987-04-21
- 发明人: Mark T. DuPriest , Billie M. York, Jr.
- 申请人： Mark T. DuPriest , Billie M. York, Jr.
- 申请人地址： TX Fort Worth
- 专利权人： Alcon Laboratories, Inc.
- 当前专利权人： Alcon Laboratories, Inc.
- 当前专利权人地址： TX Fort Worth
- 主分类号： C07D339/08
- IPC分类号： C07D339/08 ; A61K31/385 ; A61K31/095 ; A61K31/13
摘要：
Disclosed are 2,3-diamino-1,4-butanedithiol; 4,5-diamino-1,2-dithiane; and their N-acyl and N-alkyl derivatives. Also disclosed are processes for preparing the disclosed compounds; pharmaceutical compositions comprising such compounds; and a method of treatment comprising administering such compounds and compositions when an antihypertensive effect or radioprotective effect is indicated.
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