发明授权
- 专利标题： Compositions, uses and methods creating reverse micelles for the clarification of biological fluids to obtain undistorted assay of analytes following clarification
- 专利标题（中）： 用于澄清生物液体的反胶束的组合物，用途和方法，以在澄清后获得分析物的无失真测定
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申请号： US368593申请日： 1982-04-15
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公开(公告)号： US4608347A公开(公告)日： 1986-08-26
- 发明人: Victor A. Bernstam
- 申请人： Victor A. Bernstam
- 专利权人： Bernstam Victor A
- 当前专利权人： Bernstam Victor A
- 主分类号： G01N1/34
- IPC分类号： G01N1/34 ; G01N33/50 ; G01N33/92 ; G01N33/96 ; G01N1/00 ; B01F17/00
摘要：
Compositions and methods are provided for clarifying and partitioning aqueous lipid-containing specimens or samples such as lipemic serum and plasma. The compositions contain zwitterionic surfactant and water-immiscible organic solvent for lipids. The components of the compositions are selected such that they are compatible in vitro and, when constituted with aqueous specimens, do not interfere with biological or chemical activity of endogenous and exogenous analytes present in the respective specimens. The methods serve to partition the specimens into discrete aqueous and non-aqueous phases. The phases in turn can be individually assayed with respect to any of various analytes, for diagnostic or other purposes.
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