Invention Application
- Patent Title: NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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Application No.: US18701800Application Date: 2022-10-18
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Publication No.: US20250002464A1Publication Date: 2025-01-02
- Inventor: Dong-Oh YOON , Kanghyun RYOO , Hyunseung LEE , Incheol RYU , Eun Jeong JEONG , Myoungwoo LEE , Jin Woo LEE , Je Hak KIM
- Applicant: SAPIENSBIO INC.
- Applicant Address: KR Gyeonggi-do
- Assignee: SAPIENSBIO INC.
- Current Assignee: SAPIENSBIO INC.
- Current Assignee Address: KR Gyeonggi-do
- Priority: KR10-2021-0138794 20211018,KR10-2022-0133578 20221017
- International Application: PCT/KR2022/015857 WO 20221018
- Main IPC: C07D241/42
- IPC: C07D241/42 ; A61K31/498 ; A61K31/4985 ; A61K31/5377 ; A61K31/541 ; C07D401/06 ; C07D401/12 ; C07D403/06 ; C07D487/04

Abstract:
The present invention relates to a novel compound that is effective in inhibiting fibrosis. The inventors confirmed that the compound has an effect of inhibiting actin polymerization and not only reduces the levels of all types of fibrosis biomarkers but also effectively inhibits the expression of α-SMA, which is a major causative factor of fibrosis. Therefore, the novel compound according to the present invention is expected to be effectively used as a preparation having an excellent effect of alleviating and inhibiting fibrosis to prevent and treat a fibrosis disease.
Information query