A sanitizing composition is provided. The sanitizing composition includes including 0.1 wt. % to about 10 wt. % of one or more antimicrobial, antifungal, and/or antiviral agents and 0.001 wt. % to about 10 wt. % of one or more volatile acids or volatile bases. The sanitizing composition includes 0.0001 wt. % to about 5 wt. % of one or more pH indicators having a color transition pH ranging from about 2 to about 6.5 or a pH indicator having a color transition ranging from about 7.5 to about 12. The sanitizing composition includes 80 wt. % to about 98 wt. % of one or more volatile solvents. Optionally, the sanitizing composition includes one or more additives. Porous, flexible, substrates pre-saturated with the sanitizing composition and methods of use are also provided.