Invention Publication
- Patent Title: P7 Containing Nucleoside-modified mRNA-lipid Nanoparticle Lineage Vaccine for Hepatitis C Virus
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Application No.: US18577550Application Date: 2022-07-06
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Publication No.: US20240358821A1Publication Date: 2024-10-31
- Inventor: Erin Kathleen Reagan , Drew Weissman
- Applicant: The Trustees of the University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- International Application: PCT/US22/73463 2022.07.06
- Date entered country: 2024-01-08
- Main IPC: A61K39/29
- IPC: A61K39/29 ; A61K9/127 ; A61K9/51 ; A61K39/00 ; A61P31/14 ; C12N7/00

Abstract:
Described are compositions comprising a nucleoside-modified RNA molecules encoding a HCV p7 protein in combination with at least one additional HCV antigen, adjuvant, or a combination thereof, and their use for inducing an immune response against HCV.
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