- 专利标题： METHODS FOR INHIBITING ANGIOGENESIS IN A SUBJECT IN NEED THEREOF
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申请号： US18633379申请日： 2024-04-11
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公开(公告)号： US20240352152A1公开(公告)日： 2024-10-24
- 发明人: Gregory A. Demopulos , Hans-Wilhelm Schwaeble , Thomas Dudler , Larry W. Tjoelker
- 申请人： Omeros Corporation , University of Leicester
- 申请人地址： US WA Seattle
- 专利权人： Omeros Corporation,University of Leicester
- 当前专利权人： Omeros Corporation,University of Leicester
- 当前专利权人地址： US WA Seattle
- 分案原申请号： US15476154 2017.03.31
- 主分类号： C07K16/40
- IPC分类号： C07K16/40 ; A61K39/00 ; A61P27/02 ; A61P35/04
摘要：
In one aspect, the present invention provides methods for preventing, treating, reverting and/or delaying angiogenesis in a mammalian subject suffering from, or at risk for developing, an angiogenesis-dependent disease or condition, comprising administering to the subject an amount of a MASP-2 inhibitory agent effective to inhibit angiogenesis. In some embodiments of these aspects of the invention, the MASP-2 inhibitory agent is a MASP-2 antibody or fragment thereof.
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