- 专利标题： PHOSPHOR-CONTAINING DRUG ACTIVATOR KIT
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申请号： US18751743申请日： 2024-06-24
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公开(公告)号： US20240342287A1公开(公告)日： 2024-10-17
- 发明人: Harold WALDER , Frederic A. BOURKE, JR. , Zakaryae FATHI , Wayne F. BEYER , Mark OLDHAM , Justus ADAMSON , Michael NOLAN
- 申请人： IMMUNOLIGHT, LLC , DUKE UNIVERSITY
- 申请人地址： US MI Detroit
- 专利权人： IMMUNOLIGHT, LLC,DUKE UNIVERSITY
- 当前专利权人： IMMUNOLIGHT, LLC,DUKE UNIVERSITY
- 当前专利权人地址： US MI Detroit; US NC Durham
- 主分类号： A61K41/00
- IPC分类号： A61K41/00 ; A61K31/37 ; A61K45/06 ; A61N5/06 ; A61N5/10
摘要：
A kit for use in performing a cancer treatment, having a vial containing a phosphor-containing drug activator, wherein the phosphor-containing drug activator is present in the vial at a dosage level that is correlated with a size of tumor to be treated, and a container containing the vial;
wherein the phosphor-containing drug activator contains an admixture of two or more phosphors capable of emitting ultraviolet and visible light upon interaction with x-rays; where the two or more phosphors include Zn2SiO4:Mn2+ and (3Ca3(PO4)2Ca(F, Cl)2:Sb3+, Mn2+) at a ratio (Zn2SiO4:Mn2+):(3Ca3(PO4)2Ca(F, Cl)2:Sb3+, Mn2+)) of from 1:10 to 10:1; wherein each of the two or more phosphors have at least one coating selected from an ethyl cellulose coating and a diamond-like carbon coating.
wherein the phosphor-containing drug activator contains an admixture of two or more phosphors capable of emitting ultraviolet and visible light upon interaction with x-rays; where the two or more phosphors include Zn2SiO4:Mn2+ and (3Ca3(PO4)2Ca(F, Cl)2:Sb3+, Mn2+) at a ratio (Zn2SiO4:Mn2+):(3Ca3(PO4)2Ca(F, Cl)2:Sb3+, Mn2+)) of from 1:10 to 10:1; wherein each of the two or more phosphors have at least one coating selected from an ethyl cellulose coating and a diamond-like carbon coating.
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