- 专利标题： COMPOSITIONS TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND METHODS FOR MAKING AND USING THE SAME
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申请号： US18438106申请日： 2024-02-09
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公开(公告)号： US20240327538A1公开(公告)日： 2024-10-03
- 发明人: Viktoriya Dubrovskaya , Eric Johansen , Lucas Liu , Darragh MacCann , Volker Schellenberger , Milton To
- 申请人： Amunix Pharmaceuticals, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Amunix Pharmaceuticals, Inc.
- 当前专利权人： Amunix Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C07K16/30
- IPC分类号： C07K16/30 ; A61K39/00 ; A61P35/00 ; C07K16/28
摘要：
Provided herein are, inter alia, antigen-binding molecules with binding specificity to cluster of differentiation 3 T cell receptor (CD3), antigen-binding molecules with binding specificity to prostate-specific membrane antigen (PSMA), cleavable linker sequences, and protease-activatable bispecific fusion proteins such as protease-activatable T cell engagers, as well as uses and methods of treatment.
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