An example medical device includes an endoscope. The endoscope includes a handle including a central control section, one or more valves coupled to the central control section, an elongate shaft extending distally from the handle to a distal tip, wherein the elongate shaft is configured to be inserted into a body cavity, and a remote user interface operatively coupled to the central control section. The remote user interface is configured to operate the one or more valves to control a flow of fluid through the elongate shaft.