Invention Publication
- Patent Title: TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
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Application No.: US18376217Application Date: 2023-10-03
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Publication No.: US20240309387A1Publication Date: 2024-09-19
- Inventor: James Butler , Brian Bettencourt , Kallanthottathil G. Rajeev , Martin A. Maier , Klaus Charisse
- Applicant: Alnylam Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- The original application number of the division: US15695254 2017.09.05
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N9/64
Abstract:
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6 and methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as β-thalassemia or hemochromatosis.
Public/Granted literature
- US1281065A Spring-stand for looms. Public/Granted day:1918-10-08
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