发明公开
- 专利标题: CTLA-4 APTAMER CONJUGATES
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申请号: US18584707申请日: 2024-02-22
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公开(公告)号: US20240309379A1公开(公告)日: 2024-09-19
- 发明人: Hua Yu , Andreas Herrmann , Marcin Tomasz Kortylewski , Piotr Marek Swiderski
- 申请人: City of Hope
- 申请人地址: US CA Duarte
- 专利权人: City of Hope
- 当前专利权人: City of Hope
- 当前专利权人地址: US CA Duarte
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K31/713 ; A61K45/06 ; A61K47/54 ; C12N15/11 ; C12N15/115
摘要:
Provided herein are, inter alia, nucleic acid compounds useful for targeting CTLA-4-expressing cells and modulating cell activity of the CTLA-4-expressing cells. The compositions provided herein may be part of pharamceutcial compositions and may be used for treatment of cancer, inflammatory diseases, infectious diseases or metabolic diseases.
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